2022
Lexus RX 350

Starts at:
$53,200
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New 2022 Lexus RX 350
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Owner reviewed vehicle score
Safety rating
NHTSA tested vehicle score
Consumer rating
Owner reviewed vehicle score
Safety rating
NHTSA tested vehicle score
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Available trims

See the differences side-by-side to compare trims.
  • RX 350 FWD
    Starts at
    $45,920
    20 City / 27 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front Wheel Drive
    Drivetrain
    See all specs
  • RX 350 AWD
    Starts at
    $47,320
    19 City / 26 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    All Wheel Drive
    Drivetrain
    See all specs
  • RX 350 F SPORT Appearance FWD
    Starts at
    $49,400
    20 City / 27 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front Wheel Drive
    Drivetrain
    See all specs
  • RX 350 F SPORT Appearance AWD
    Starts at
    $50,800
    19 City / 26 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    All Wheel Drive
    Drivetrain
    See all specs
  • RX 350 F SPORT Handling FWD
    Starts at
    $51,800
    20 City / 27 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front Wheel Drive
    Drivetrain
    See all specs
  • RX 350 F SPORT Handling AWD
    Starts at
    $53,200
    19 City / 26 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    All Wheel Drive
    Drivetrain
    See all specs

Photo & video gallery

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Notable features

Gas (RX 350) and hybrid (RX 450h) models
Three-row L version available
Front- or all-wheel drive
Touchscreen multimedia system with Android Auto, Apple CarPlay
Limited-edition Black Line models available

The good & the bad

The good

Overall refinement
Cabin materials
Seat comfort (base and luxury models)
Lack of touch-sensitive buttons
Smooth, quiet operation (base model)

The bad

Leather seats not standard
Feels heavy in corners
Uninspiring braking feel
Maddening multimedia controller
Stiffly bolstered seats (F Sport)

Expert 2022 Lexus RX 350 review

our expert's take
Our expert's take
By Cars.com Editors
Full article
our expert's take

What Is the 2022 Lexus RX?

The five-seat Lexus RX mid-size luxury SUV is available in gas RX 350 or hybrid RX 450h form. There’s also a performance-oriented F Sport model and a three-row L version that seats up to seven. All use a 3.5-liter V-6 engine, and the RX 450h adds electric motors.

The RX 350 is available with front- or all-wheel drive. The RX 450h is all-wheel-drive only, with an electric motor driving the rear wheels. Competitors include the Cadillac XT5, Acura MDX and Infiniti QX60.

What’s New on the 2022 Lexus RX?

There are no significant changes this year.

What Features in the 2022 Lexus RX Are Most Important?

Standard features include:

  • 18-inch aluminum wheels
  • LED headlights
  • Dual-zone automatic air conditioning
  • 8-inch touchscreen multimedia system
  • Android Auto and Apple CarPlay smartphone connectivity
  • Forward collision warning
  • Automatic emergency braking
  • Lane-keeping assist
  • Adaptive cruise control
  • Blind spot warning with rear cross-traffic alert

Available features include:

  • Panoramic moonroof
  • Hands-free power liftgate
  • Leather-trimmed interior
  • Heated and ventilated front seats
  • Heated second-row seats
  • Heated steering wheel
  • Head-up display
  • Navigation with 12.3-inch touchscreen
  • Mark Levinson premium stereo
  • Rear automatic braking

Should I Buy the 2022 Lexus RX?

Often credited with creating the luxury crossover SUV class, the Lexus RX continues to please buyers looking for refinement, but our editors find it less engaging to drive than some competitors. The Remote Touch multimedia interface remains frustrating, but the inclusion of a touchscreen makes it less of an issue than it was previously. The cramped third row in extended L versions is of dubious usefulness.

2022 Lexus RX 350 review: Our expert's take

What Is the 2022 Lexus RX?

The five-seat Lexus RX mid-size luxury SUV is available in gas RX 350 or hybrid RX 450h form. There’s also a performance-oriented F Sport model and a three-row L version that seats up to seven. All use a 3.5-liter V-6 engine, and the RX 450h adds electric motors.

The RX 350 is available with front- or all-wheel drive. The RX 450h is all-wheel-drive only, with an electric motor driving the rear wheels. Competitors include the Cadillac XT5, Acura MDX and Infiniti QX60.

What’s New on the 2022 Lexus RX?

There are no significant changes this year.

What Features in the 2022 Lexus RX Are Most Important?

Standard features include:

  • 18-inch aluminum wheels
  • LED headlights
  • Dual-zone automatic air conditioning
  • 8-inch touchscreen multimedia system
  • Android Auto and Apple CarPlay smartphone connectivity
  • Forward collision warning
  • Automatic emergency braking
  • Lane-keeping assist
  • Adaptive cruise control
  • Blind spot warning with rear cross-traffic alert

Available features include:

  • Panoramic moonroof
  • Hands-free power liftgate
  • Leather-trimmed interior
  • Heated and ventilated front seats
  • Heated second-row seats
  • Heated steering wheel
  • Head-up display
  • Navigation with 12.3-inch touchscreen
  • Mark Levinson premium stereo
  • Rear automatic braking

Should I Buy the 2022 Lexus RX?

Often credited with creating the luxury crossover SUV class, the Lexus RX continues to please buyers looking for refinement, but our editors find it less engaging to drive than some competitors. The Remote Touch multimedia interface remains frustrating, but the inclusion of a touchscreen makes it less of an issue than it was previously. The cramped third row in extended L versions is of dubious usefulness.

Available cars near you

Safety review

Based on the 2022 Lexus RX 350 base trim
NHTSA crash test and rollover ratings, scored out of 5.
Overall rating
4/5
Combined side rating front seat
5/5
Combined side rating rear seat
5/5
Frontal barrier crash rating driver
3/5
Frontal barrier crash rating passenger
4/5
Overall frontal barrier crash rating
4/5
Overall side crash rating
5/5
Rollover rating
4/5
Side barrier rating
5/5
Side barrier rating driver
5/5
Side barrier rating passenger rear seat
5/5
Side pole rating driver front seat
5/5
16.4%
Risk of rollover
Side barrier rating driver
5/5
Side barrier rating passenger rear seat
5/5
Side pole rating driver front seat
5/5
16.4%
Risk of rollover

Factory warranties

New car program benefits

Basic
4 years / 50,000 miles
Corrosion
6 years
Powertrain
6 years / 70,000 miles
Maintenance
1 years / 10,000 miles
Roadside Assistance
4 years

Certified Pre-Owned program benefits

Age / mileage
2 years / unlimited miles from your certified vehicle date of purchase.
Basic
2 years / unlimited miles from your certified vehicle date of purchase. Coverage begins after completion of the 4-year / 50,000 new vehicle Basic Warranty.
Dealer certification
161-point inspection

Compare similar vehicles

Select cars to compare for more detailed info.
  • 2022
    3.9
    Lexus RX 350
    Starts at
    $45,920
    20 City / 27 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front-wheel drive
    Drivetrain
    Compare
  • 2020
    5.0
    Lexus RX 350L
    Starts at
    $47,300
    19 City / 26 Hwy
    MPG
    6
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front-wheel drive
    Drivetrain
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  • 2021
    4.6
    Lexus RX 350
    Starts at
    $45,220
    20 City / 27 Hwy
    MPG
    5
    Seat capacity
    Regular Unleaded V-6
    Engine
    Front-wheel drive
    Drivetrain
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    4.0
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    $41,750
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    MPG
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    Seat capacity
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  • 2022
    4.5
    Acura MDX
    Starts at
    $48,000
    19 City / 26 Hwy
    MPG
    7
    Seat capacity
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    Front-wheel drive
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  • 2023
    4.7
    Toyota Venza
    Starts at
    $34,620
    40 City / 37 Hwy
    MPG
    5
    Seat capacity
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    Engine
    All-wheel drive
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  • 2021
    4.4
    Mercedes-Benz GLE 350
    Starts at
    $54,750
    19 City / 26 Hwy
    MPG
    7
    Seat capacity
    Intercooled Turbo Premium Unleaded I-4
    Engine
    Rear-wheel drive
    Drivetrain
    Compare
  • Compare more options
    Use our comparison tool to add any vehicle of your choice and see a full list of specifications and features side-by-side.
    Try it now

Consumer reviews

3.9 / 5
Based on 11 reviews
Write a review
Comfort 4.5
Interior 4.5
Performance 3.8
Value 3.5
Exterior 4.6
Reliability 3.9

Most recent

Great Car

This is my second Lexus. I originally had an ES 350 which was a wonderful car. I am very happy with the Lexus RX It drives nicely, is roomy, spacious, comfortable, and is an excellent car to own
  • Purchased a New car
  • Used for Transporting family
  • Does recommend this car
Comfort 5.0
Interior 5.0
Performance 5.0
Value 5.0
Exterior 5.0
Reliability 5.0
6 people out of 6 found this review helpful. Did you?
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Poor hard shifting and surging/not starting

Bought a brand new 2022 Rx 350, Car has had issues with hard down and up shifting/surging-to the point of almost getting rear ended. Then the intermittent not starting happened with 1980's infotainment system lighting up and nothing when foot on brake pedal, which is getting worse now at 24k and needing to re sync key and a couple tries later, will start-NOT reliable. Don't even get me started on the rear hatch sensor-a million dollars couldn't get me to open it. I'm seeing all these other customers complaining at the dealerships over the shifting issues and online-can't be just me!
  • Purchased a New car
  • Used for Commuting
  • Does not recommend this car
Comfort 2.0
Interior 1.0
Performance 1.0
Value 1.0
Exterior 2.0
Reliability 1.0
14 people out of 16 found this review helpful. Did you?
Yes No

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FAQ

What trim levels are available for the 2022 Lexus RX 350?

The 2022 Lexus RX 350 is available in 3 trim levels:

  • RX 350 (2 styles)
  • RX 350 F SPORT Appearance (2 styles)
  • RX 350 F SPORT Handling (2 styles)

What is the MPG of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 offers up to 20 MPG in city driving and 27 MPG on the highway. These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on vehicle options, trim level, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2022 Lexus RX 350?

The 2022 Lexus RX 350 compares to and/or competes against the following vehicles:

Is the 2022 Lexus RX 350 reliable?

The 2022 Lexus RX 350 has an average reliability rating of 3.9 out of 5 according to cars.com consumers. Find real-world reliability insights within consumer reviews from 2022 Lexus RX 350 owners.

Is the 2022 Lexus RX 350 a good SUV?

Below are the cars.com consumers ratings for the 2022 Lexus RX 350. 63.6% of drivers recommend this vehicle.

3.9 / 5
Based on 11 reviews
  • Comfort: 4.5
  • Interior: 4.5
  • Performance: 3.8
  • Value: 3.5
  • Exterior: 4.6
  • Reliability: 3.9

Lexus RX 350 history

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