2006
Mercedes-Benz S-Class

Starts at:
$77,250
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New 2006 Mercedes-Benz S-Class
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NHTSA tested vehicle score
Consumer rating
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NHTSA tested vehicle score
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Available trims

See the differences side-by-side to compare trims.
  • 4dr Sdn 3.7L
    Starts at
    $64,900
    17 City / 25 Hwy
    MPG
    5
    Seat capacity
    Gas V6
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 4.3L
    Starts at
    $77,250
    17 City / 26 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 4.3L 4MATIC
    Starts at
    $77,250
    17 City / 22 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    All Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 5.0L
    Starts at
    $86,050
    16 City / 24 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 5.0L 4MATIC
    Starts at
    $86,050
    16 City / 22 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    All Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 5.5L AMG
    Starts at
    $114,150
    15 City / 22 Hwy
    MPG
    4
    Seat capacity
    Gas V8
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 5.5L
    Starts at
    $127,950
    12 City / 19 Hwy
    MPG
    4
    Seat capacity
    Gas V12
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs
  • 4dr Sdn 6.0L AMG
    Starts at
    $169,000
    13 City / 20 Hwy
    MPG
    4
    Seat capacity
    Gas V12
    Engine
    Rear Wheel Drive
    Drivetrain
    See all specs

Photo & video gallery

2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class 2006 Mercedes-Benz S-Class

Notable features

Six potent powertrain choices
RWD or AWD
New 604-hp S65 AMG
Mercedes-Benz pedigree
Seven-speed automatic in S430s and S500s with RWD

The good & the bad

The good

Performance in S600 and AMG models
Luxury amenities
Stability
Refinement
Resale value of S55 AMG

The bad

Price
Fuel economy
Control layout and complexity
See all specifications

Available cars near you

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Factory warranties

New car program benefits

Basic
4 years / 50,000 miles
Corrosion
4 years / 50,000 miles
Powertrain
4 years / 50,000 miles

Certified Pre-Owned program benefits

Age / mileage
6 years old or less / less than 75,000 miles
Basic
1 year / unlimited miles
Dealer certification
164-point inspection
See all CPO program details

Compare similar vehicles

Select cars to compare for more detailed info.
  • 2006
    4.5
    Mercedes-Benz S-Class
    Starts at
    $64,900
    17 City / 25 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    Rear-wheel drive
    Drivetrain
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  • 2014
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    Aston Martin DB9
    Starts at
    $183,700
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    MPG
    2
    Seat capacity
    Premium Unleaded V-12
    Engine
    Rear-wheel drive
    Drivetrain
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  • 2018
    Mercedes-Benz Maybach S 650
    Starts at
    $198,700
    13 City / 21 Hwy
    MPG
    4
    Seat capacity
    Twin Turbo Premium Unleaded V-12
    Engine
    Rear-wheel drive
    Drivetrain
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  • 2004
    4.8
    Mercedes-Benz S-Class
    Starts at
    $74,250
    18 City / 26 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    Rear-wheel drive
    Drivetrain
    Compare
  • 2008
    5.0
    Bentley Continental Flying Spur
    Starts at
    $170,990
    10 City / 17 Hwy
    MPG
    4
    Seat capacity
    Gas W12
    Engine
    All-wheel drive
    Drivetrain
    Compare
  • 1999
    5.0
    BMW 740
    Starts at
    $62,400
    17 City / 23 Hwy
    MPG
    5
    Seat capacity
    Gas V8
    Engine
    Rear-wheel drive
    Drivetrain
    Compare
  • 2000
    5.0
    Mercedes-Benz CL-Class
    Starts at
    $85,500
    16 City / 23 Hwy
    MPG
    4
    Seat capacity
    Gas V8
    Engine
    Rear-wheel drive
    Drivetrain
    Compare
  • Compare more options
    Use our comparison tool to add any vehicle of your choice and see a full list of specifications and features side-by-side.
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Consumer reviews

92% of drivers recommend this car
4.5 / 5
Based on 40 reviews
Write a review
Comfort 4.9
Interior 4.6
Performance 4.7
Value 4.4
Exterior 4.7
Reliability 4.3

Most recent

By 4Benzowner from Menifee CA
Owns this car
November 24, 2022

2006 S430 Low price low miles, Unbelievable value

recently just bought a super low mileage 2006 S430 California one owner car, that had been pampered and garaged. Beautiful flawless interior, gorgeous exterior with AMG sport package and new tires. Car had around 87000 miles on it, so I didn't squabble over 10k price, it also had new tires. I own another 2009 S550 but couldn't resist buying this one as it was last year of the body style and this one had wonderful service records. Engine shifts perfectly, AC blows cold, fresh oil change, it is a really great car for the money and you simply cannot buy a car of this high quality for this amount of money.
  • Purchased a Used car
  • Used for Commuting
  • Does recommend this car
Comfort 5.0
Interior 5.0
Performance 5.0
Value 5.0
Exterior 5.0
Reliability 5.0
11 people out of 13 found this review helpful. Did you?
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By previous MB Owner from Annapolis , MD
Used to own this car
July 10, 2020

Great on long trips and commuting in traffic

This car is the best i ever owned, always attention from others , many compliments while filling up at gas station. i had a AMG package on my previous 2006 S 500. I had 230k mileages on it. always dealer maintained . I lost it as engine caught as result of oil. change at dealership in Annapolis MD. drove 30 min home and fire happened. However i must say not my fault or cars. just got a bad tech , I would still recommend this vehicle . I have dropped out of the Mercedes family because of poor service locally.
  • Purchased a Used car
  • Used for Commuting
  • Does recommend this car
Comfort 5.0
Interior 4.0
Performance 4.0
Value 4.0
Exterior 5.0
Reliability 4.0
8 people out of 8 found this review helpful. Did you?
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Mercedes-Benz dealers near you

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FAQ

What trim levels are available for the 2006 Mercedes-Benz S-Class?

The 2006 Mercedes-Benz S-Class is available in 6 trim levels:

  • 3.7L (1 style)
  • 4.3L (2 styles)
  • 5.0L (2 styles)
  • 5.5L (1 style)
  • 5.5L AMG (1 style)
  • 6.0L AMG (1 style)

What is the MPG of the 2006 Mercedes-Benz S-Class?

The 2006 Mercedes-Benz S-Class offers up to 17 MPG in city driving and 25 MPG on the highway. These figures are based on EPA mileage ratings and are for comparison purposes only. The actual mileage will vary depending on vehicle options, trim level, driving conditions, driving habits, vehicle maintenance, and other factors.

What are some similar vehicles and competitors of the 2006 Mercedes-Benz S-Class?

The 2006 Mercedes-Benz S-Class compares to and/or competes against the following vehicles:

Is the 2006 Mercedes-Benz S-Class reliable?

The 2006 Mercedes-Benz S-Class has an average reliability rating of 4.3 out of 5 according to cars.com consumers. Find real-world reliability insights within consumer reviews from 2006 Mercedes-Benz S-Class owners.

Is the 2006 Mercedes-Benz S-Class a good Sedan?

Below are the cars.com consumers ratings for the 2006 Mercedes-Benz S-Class. 92.5% of drivers recommend this vehicle.

4.5 / 5
Based on 40 reviews
  • Comfort: 4.9
  • Interior: 4.6
  • Performance: 4.7
  • Value: 4.4
  • Exterior: 4.7
  • Reliability: 4.3

Mercedes-Benz S-Class history

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